Trigonelline Reverses Lung Scarring in Rats.
This study evaluates trigonelline, a natural compound, to remedy lung scarring in rats. It was tested alone or combined with Pirfenidone (Pirf), a clinically approved, but not well-tolerated drug to treat lung damage. “Following the COVID-19 outbreak and the limitation of the current therapies for PF, the burden of pulmonary fibrotic disease is expected to…